Clinical Pediatric Emergency Medicine
Volume 6, Issue 3 , Pages 156-164 , September 2005

Tumors of the Mediastinum

  • Stephanie S. Kennebeck, MD

      Affiliations

    • Corresponding Author InformationReprint requests and correspondence: Stephanie S. Kennebeck, MD, Division of Pediatric Emergency Medicine, Cincinnati Children's Hospital Medical Center, University of Cincinnati College of Medicine, 3333 Burnet Avenue, MLC 2008, Cincinnati, OH 45229.

References 

  1. Fraser RS, Pare JP, Fraser RG, et al. The normal chest. In:  Fraser RS,  Pare JP,  Fraser RG editor. Synopsis of diseases of the chest. 2nd ed.. Philadelphia (Pa): Saunders; 1994;p. 1–116
  2. Lau CL, Davis RD. The mediastinum. In:  Townsend CM,  Beauchamp RD,  Evers BM,  Mattox KL editor. 17th ed.. Sabiston Textbook of Surgery. vol. 1:Philadelphia (Pa): WB Saunders; 2004;p. 1738–1759
  3. King RM, Telander RL, Smithson WA, et al. Primary mediastinal tumors in children. J Pediatr Surg. 1982;17:512–520
  4. Azizkhan RG, Dudgeon DL, Buck JR, et al. Life-threatening airway obstruction as a complication to the management of mediastinal masses in children. J Pediatr Surg. 1985;20:816–820
  5. Link MP, Donaldson SS. The lymphomas and lymphadenopathy. In:  Nathan DG editors. 5th ed.. Nathan and Oski's hematology of infancy and childhood. vol. 2:Philadelphia (Pa): WB Saunders; 1998;p. 1323–1358
  6. Saenz NC, Schnitzer JJ, Eraklis AE, et al. Posterior mediastinal masses. J Pediatr Surg. 1993;28:172–176
  7. Takeda S, Miyoshi S, Minami M, et al. Clinical spectrum of primary mediastinal tumors: a comparison of adult and pediatric populations. Chest. 2000;118:206s;[abstr]
  8. Freud E, Ben-Ari J, Schonfeld T, et al. Mediastinal tumors in children: a single institution experience. Clin Pediatr. 2002;41:219–223
  9. Grosfeld JL, Skinner MA, Rescorla FJ, et al. Mediastinal tumors in children: experience with 196 cases. Ann Surg Oncol. 1994;1:121–127
  10. Piastra M, Caresta E, Ruggiero A, et al. Management of critically ill children with mediastinal neoplasms: a 6-year survey from a single institution. Am J Emerg Med. 2005;23:329–331
  11. Haller JA, Mazur DO, Morgan WW. Diagnosis and management of mediastinal masses in children. J Thorac Cardiovasc Surg. 1969;58:385–393
  12. Azarow KS, Pearl RH, Zurcher R, et al. Primary mediastinal masses. A comparison of adult and pediatric populations. J Thorac Cardiovasc Surg. 1993;106:67–72
  13. Thompson DP, Moore TC. Acute thoracic distress in childhood due to spontaneous rupture of a large mediastinal teratoma. J Pediatr Surg. 1969;4:416–423
  14. Strollo DC, Rosado de Christenson ML, Jett JR. Primary mediastinal tumors, Part 1. Tumors of the anterior mediastinum. Chest. 1997;112:511–522
  15. Nichols CR. Mediastinal germ cell tumors: clinical features and biologic correlates. Chest. 1991;99:472–479
  16. Kaplinsky C, Mor C, Cohen IJ, et al. Childhood malignant thymoma: clinical, therapeutic, and immunohistochemical considerations. Pediatr Hematol Oncol. 1992;9:261–268
  17. Spigland N, Di Lorenzo M, Youssef S, et al. Malignant thymoma in children: a 20-year review. J Pediatr Surg. 1990;25:1143–1146
  18. Mandell GA, Lantieri R, Goldman LR. Tracheobronchial compression in Hodgkin lymphoma in children. AJR Am J Roentgenol. 1982;139:1167–1170
  19. Lanzkowsky P. Hodgkin's disease. In:  Lanzkowski P editors. 2nd ed.. Manual of pediatric hematology and oncology. vol 1:New York (NY): Churchill Livingstone; 1997;p. 351–359
  20. Armatta J, Balwierz W, Moryl-Bujakowska A, et al. Childhood stage IV Hodgkin disease: therapeutic results of the Polish leukemia/lymphoma study group. Med Pediatr Oncol. 1999;33:382–387
  21. Attarbashi A, Mann G, Dworzak M, et al. Mediastinal mass in childhood T-cell acute lymphoblastic leukemia: significance and therapy response. Med Pediatr Oncol. 2002;39:558–565
  22. Shad A, Magrath I. Non-Hodgkin's lymphoma. Pediatr Clin N Am. 1997;44:863–890
  23. Strollo DC, Rosado de Christenson ML, Jett JR. Tumors of the middle and posterior mediastinum. Chest. 1997;112:1344–1358
  24. Superina RA, Ein SH, Humphreys RP. Cystic duplications of the esophagus and neuroenteric cysts. J Pediatr Surg. 1984;19:527–530
  25. Macchiarini P, Ostertag H. Uncommon primary mediastinal tumours. Lancet Oncol. 2004;5:107–118
  26. Kelly KM, Lange B. Oncologic emergencies. Pediatr Clin N Am. 1997;44:809–830
  27. Maguire WM. Mechanical complications of cancer. Emerg Med Clin North Am. 1993;11:421–430
  28. Bertsch H, Rodoler S, Needle MN, et al. Emergent/urgent therapeutic irradiation in pediatric oncology: patterns of presentation. Med Pediatr Oncol. 1998;30:101–105
  29. D'angio GJ, Mitus A, Evans AE. The superior mediastinal syndrome in children with cancer. AJR Am J Roentgenol. 1975;93:537–543
  30. Issa PY, Brihi ER, Janin Y, et al. Superior vena cava syndrome in childhood: report of ten cases and review of the literature. Pediatrics. 1983;71:337–341
  31. Shamberger RC, Holzman RS, Grisco NT, et al. CT quantification of tracheal cross-sectional area as a guide to the surgical and anesthetic management of children with anterior mediastinal masses. J Pediatr Surg. 1991;26:138–142
  32. Lewis DW, Packer RJ, Raney D, et al. Incidence, presentation, and outcome of spinal cord disease in children with systemic cancer. Pediatrics. 1986;78:438–442
  33. Piastra M, Ruggiero A, Caresta E, et al. Life-threatening presentation of mediastinal neoplasms: report on 7 consecutive pediatric patients. Am J Emerg Med. 2005;23:76–82
  34. Piro AH, Weiss DR, Hellman S. Mediastinal Hodgkin's disease: a possible danger for intubation anesthesia. Int J Radiat Oncol Biol Phys. 1976;1:415–419
  35. Hammer GB. Anaesthetic management for the child with a mediastinal mass. Pediatr Anesth. 2004;14:95–97
  36. Shamberger RC, Holzman RS, Griscom NT, et al. Prospective evaluation by computed tomography and pulmonary function tests of children with mediastinal masses. Surgery. 1995;118:468–471
  37. Ponder TB, Smith D, Ramzy I. Lymphadenopathy in children and adolescents: role of fine-needle aspiration in management. Cancer Detect Prev. 2000;24:228–233
  38. Twist CJ, Link MP. Assessment of lymphadenopathy in children. Pediatr Clin North Am. 2002;49:1009–1025
  39. Chaignaud BE, Bonsack TA, Kozakewich HP, et al. Pleural effusions in lymphoblastic lymphoma: a diagnostic alternative. J Pediatr Surg. 1998;33:1355–1357
  40. Pietsch JB, Whitlock JA, Ford C, et al. Management of pleural effusions in children with malignant lymphoma. J Pediatr Surg. 1999;34:635–638
  41. Yu CJ, Yang PC, Chang DB, et al. Evaluation of ultrasonically guided biopsies of mediastinal masses. Chest. 1991;100:399–405
  42. Yang PC, Lee YC, Yu CJ, et al. Ultrasonographically guided biopsy of thoracic tumors. A comparison of large-bore cutting biopsy with fine-needle aspiration. Cancer. 1992;69:2553–2560
  43. Glick RD, Pearse IA, Trippett T, et al. Diagnosis of mediastinal masses in pediatric patients using mediastinoscopy and the Chamberlain procedure. J Pediatr Surg. 1999;34:559–564
  44. King DR, Patrick LE, Ginn-Pease ME, et al. Pulmonary function is compromised in children with mediastinal lymphoma. J Pediatr Surg. 1997;32:294–300

PII: S1522-8401(05)00077-7

doi: 10.1016/j.cpem.2005.05.003

Clinical Pediatric Emergency Medicine
Volume 6, Issue 3 , Pages 156-164 , September 2005